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Gene Report for SPG00001175_2.0
Identity
Gene
Glutathione peroxidase 5 (GPx5)
Species
Loxodonta africana
(Elephant)
Description
This gene belongs to the glutathione peroxidase family. It is specifically expressed in the epididymis in the mammalian male reproductive tract, and is androgen-regulated. Unlike mRNAs for other characterized glutathione peroxidases, this mRNA does not contain a selenocysteine (UGA) codon. Thus, the encoded protein is selenium-independent, and has been proposed to play a role in protecting the membranes of spermatozoa from the damaging effects of lipid peroxidation and/or preventing premature acrosome reaction. (
NCBI
)
Family
Glutathione peroxidase
Synonyms
None
Subfamily
Glutathione peroxidase 5 (GPx5)
Synonyms
None
Gene ID
SPG00001175
Gene release
2.0
External ID
None
Annotation
Prediction method(s)
Promoter prediction (5000bp upstream, N/A)
[
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]
(Selenoprofiles, Ensembl 68)
[
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]
Conceptual translation (Translate, Standard code with Sec)
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]
Orientation
Reverse
Structure
Feature
Col
Promoter
Col
Coding exon
Col
Non coding exon (UTR)
Col
Intron
Col
SECIS
Residue
Col
Sec
Col
Cys or Other
Gene
Transcript(s)
Promoter(s)
Protein(s)
Secis
SPT00001271_2.0
SPR00001336_2.0
SPP00001279_2.0
N/A
Sequence
Sequence
SEQ00001174_2.0
External ID
None
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Cite
S. Castellano, V.N. Gladyshev, R. Guigó and M.J. Berry
SelenoDB: a database of selenoprotein genes, proteins and SECIS elements
Unpublished
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